Sorting Nexin 4 antibody (AA 351-450) (Alexa Fluor 488)

Catalog No. ABIN1694950

Product Details anti-Sorting Nexin 4 Antibody (Alexa Fluor 488)

Target: Sorting Nexin 4 (SNX4)

Binding Specificity: AA 351-450

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Sorting Nexin 4 antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNX4

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Sorting Nexin 4

Target: Sorting Nexin 4 (SNX4)

Alternative Name: SNX4 (SNX4 Products)

Synonyms: ATG24B antibody, 1810036H14Rik antibody, AI037066 antibody, im:6971267 antibody, wu:fb92d09 antibody, zgc:113437 antibody, SNX4 antibody, LOC100221641 antibody, sorting nexin 4 antibody, Snx4p antibody, SNX4 antibody, Snx4 antibody, snx4 antibody

Background:

Synonyms: ATG24B, SNX 4, snx4, SNX4_HUMAN, Sorting nexin 4, Sorting nexin-4.

Background: SNX2 and SNX4 share a high degree of amino acid similarity with SNX1, as they all contain a characteristic phox homology (PX) domain (4). These proteins are all partially associated with cellular membranes, and they, likewise, associate with EGF, PDGF and insulin receptor tyrosine kinases (2). These nexins are widely expressed and yet have various tissue distribution patterns. Additionally, the sorting nexins can associate with each other and with a variety of other cellular proteins, suggesting that they exist as part of multisubunit complexes (1,5). The related protein, SNX3, comprises a distinct subgroup of nexins that share less sequence similarity outside of the PX domain and have dramatically different binding affinities for the tyrosine kinase receptors (2,6).

Gene ID: 8723