AKTIP antibody (AA 201-292) (Alexa Fluor 488)

Catalog No. ABIN1695216

Product Details anti-AKTIP Antibody (Alexa Fluor 488)

Target: AKTIP (AKT Interacting Protein (AKTIP))

Binding Specificity: AA 201-292

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AKTIP antibody is conjugated to Alexa Fluor 488

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FTS/AKTIP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for AKTIP

Target: AKTIP (AKT Interacting Protein (AKTIP))

Alternative Name: FTS/AKTIP (AKTIP Products)

Synonyms: FT1 antibody, FTS antibody, cb798 antibody, fts antibody, zgc:77699 antibody, fts-A antibody, aktip antibody, fts-B antibody, MGC133931 antibody, AL023020 antibody, Fif antibody, Ft antibody, Ft1 antibody, Fts antibody, AKT interacting protein antibody, akt interacting protein antibody, AKT interacting protein L homeolog antibody, AKT interacting protein S homeolog antibody, thymoma viral proto-oncogene 1 interacting protein antibody, AKTIP antibody, aktip antibody, aktip.L antibody, aktip.S antibody, Aktip antibody

Background:

Synonyms: AKT interacting protein, AKT-interacting protein, AKTIP, AKTIP_HUMAN, FT 1, FT1, Fused toes homolog, Fused toes protein homolog.

Background: Fused toes protein homolog (FTS), also known as AKT-interacting protein (AKTIP) and Ft1, is a 292 amino acid protein that localizes to the cytoplasm and the cell membrane. A member of the ubiquitin-conjugating enzyme family, FTS binds directly to AKT1 to regulate apoptosis in a cell population. AKT1 is a protein that plays a critical role in a number of cellular responses, such as cell growth, protein synthesis, and antiapoptotic signaling. The interaction of FTS and AKT1 enhances the phosphorylation and activation of AKT1, which, through an AKT1/GSK-3/NFATc1 signaling cascade, results in the increased production of the proapoptotic hormone Fas ligand and thus an increase in apoptosis.

Gene ID: 64400