NPBWR1 antibody (AA 1-100) (Alexa Fluor 555)

Catalog No. ABIN1696704

Product Details anti-NPBWR1 Antibody (Alexa Fluor 555)

Target: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Binding Specificity: AA 1-100

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NPBWR1 antibody is conjugated to Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Mouse

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GPR7

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NPBWR1

Target: NPBWR1 (Neuropeptides B/W Receptor 1 (NPBWR1))

Alternative Name: GPR7 (NPBWR1 Products)

Synonyms: NPBWR1 antibody, GPR7 antibody, Gpr7 antibody, Nbpwr1 antibody, neuropeptides B/W receptor 1 antibody, neuropeptides B and W receptor 1 antibody, NPBWR1 antibody, Npbwr1 antibody

Background:

Synonyms: GPCR GPR7, G protein coupled receptor 7, g protein coupled receptor gpr7, GPR7, MGC129755, Neuropeptides B and W receptor 1, Neuropeptides B/W receptor 1, Neuropeptides B/W receptor type 1, NPB and NPW receptor 1, NPBWR1, opioid somatostatin like receptor 7.

Background: The two G protein-coupled receptors GPR7 and GPR8 display high similarity to each other. They both show high expression in brain and in particular in hypothalamus, and have been characterized as receptors for neuropeptide W (NPW) and neuropeptide B (NPB). In response to NPW and NPB, they play a role in the regulation of feeding behavior. GPR7 deficient mice develop an adult-onset obese phenotype that progressively worsens with age and is exacerbated when fed a high-fat diet. The genes encoding human GPR7 and GPR8 map to chromosomes 10q11.2-q21.1 and 10q13.3, respectively.

Gene ID: 2831