MSY2/ YBOX2/ DBPC (AA 101-185) antibody (Alexa Fluor 647)

Catalog No. ABIN1699578

Product Details

Target: MSY2/ YBOX2/ DBPC

Binding Specificity: AA 101-185

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human YBOX2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: MSY2/ YBOX2/ DBPC

Alternative Name: MSY2/YBOX2/DBPC

Background:

Synonyms: Contrin, CSDA 3, CSDA3, DBPC, DNA binding protein C, DNA-binding protein C, FRGY2 homolog, Germ cell specic Y box binding protein, Germ cell-specic Y-box-binding protein, MGC118270, MGC45104, MSY 2, MSY2, MSY2 homolog, OTTMUSP00000006276, RGD1305068, Y box binding protein 2, Y-box-binding protein 2, YBOX2_HUMAN, YBX 2, YBX2.

Background: MSY2 and YB-2 (MSY3,4) belong to the Y-box family of multifunctional proteins that regulate both transcription and translation (13). Y-box proteins interact with a wide variety of nucleic acid structures to act as transcription factors and mRNA masking proteins (1). The modular structure of Y-box proteins includes a highly conserved N-terminal cold-shock domain (CSD, equivalent to the bacterial cold-shock proteins) and four basic C-terminal domains containing arginine clusters and aromatic residues (4). MSY2 is expressed in testis and ovary where it may repress translation of parental mRNA (5,6). The gene encoding human MSY2 maps to chromosome 17p11.2-13.1 (5). YB-2 (MSY3,4 in mouse) is also known as DNA binding protein A and is highly expressed in the testis, heart and muscle (7,8). MSY2 and YB-2 bind to the consensus sequence 5'-UCCAUCA-3' contained in the Y-box element (9).

Gene ID: 51087