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C1orf85 antibody (AA 51-150) (Cy5.5)

C1ORF85 Reactivity: Human WB, IF (cc), IF (p) Host: Rabbit Polyclonal Cy5.5
Catalog No. ABIN1706577
  • Target See all C1orf85 (C1ORF85) Antibodies
    C1orf85 (C1ORF85) (Chromosome 1 Open Reading Frame 85 (C1ORF85))
    Binding Specificity
    • 14
    • 2
    • 1
    AA 51-150
    Reactivity
    • 14
    • 3
    • 1
    Human
    Host
    • 16
    • 1
    Rabbit
    Clonality
    • 17
    Polyclonal
    Conjugate
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This C1orf85 antibody is conjugated to Cy5.5
    Application
    • 17
    • 12
    • 12
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Predicted Reactivity
    Human,Mouse,Rat,Dog,Cow,Sheep,Horse
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf85
    Isotype
    IgG
    Top Product
    Discover our top product C1ORF85 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    C1orf85 (C1ORF85) (Chromosome 1 Open Reading Frame 85 (C1ORF85))
    Alternative Name
    C1orf85 (C1ORF85 Products)
    Synonyms
    NCU-G1 antibody, C1orf85 antibody, 0610031j06rik antibody, AB027141 antibody, CA085 protein antibody, glycosylated lysosomal membrane protein antibody, glmp antibody, GLMP antibody, Glmp antibody
    Background

    Synonyms: C1orf85, Chromosome 1 open reading frame 85, Lysosomal protein NCU-G1, NCUG1_HUMAN, PSEC0030, UNQ2553/PRO6182.

    Background: C1orf85, also known as Lysosomal protein NCU-G1, is a 406 amino acid single-pass membrane protein that is highly glycosylated on its amino-terminal end. Transcription of the gene encoding C1orf85 is activated by TFEB, a transcription factor that specifically recognizes and binds E-box sequences. There are two isoforms of C1orf85 that are produced as a result of alternative splicing events. The C1orf85 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8 % of the human genome. There are about 3,000 genes on chromosome 1, and considering the great number of genes there are also a large number of diseases associated with chromosome 1. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A. When defective, the LMNA gene product can build up in the nucleus and cause characteristic nuclear blebs. The mechanism of rapidly enhanced aging is unclear and is a topic of continuing exploration. The MUTYH gene is located on chromosome 1 and is partially responsible for familial adenomatous polyposis. Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome are also associated with chromosome 1.

    Gene ID
    112770
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