ZBTB4 antibody (AA 301-400) (HRP)

Catalog No. ABIN1712412

Product Details anti-ZBTB4 Antibody (HRP)

Target: ZBTB4 (Zinc Finger and BTB Domain Containing 4 (ZBTB4))

Binding Specificity: AA 301-400

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ZBTB4 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human ZBTB4/ZNF903

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for ZBTB4

Target: ZBTB4 (Zinc Finger and BTB Domain Containing 4 (ZBTB4))

Alternative Name: ZBTB4/ZNF903 (ZBTB4 Products)

Synonyms: KAISO-L1 antibody, ZNF903 antibody, 2310026P19Rik antibody, 9230111I22Rik antibody, RP23-422L16.16 antibody, mKIAA1538 antibody, zinc finger and BTB domain containing 4 antibody, ZBTB4 antibody, Zbtb4 antibody

Background:

Synonyms: KAISO-L1, KAISO-like zinc finger protein 1, KIAA1538, ZBTB4, ZBTB4_HUMAN, Zinc finger and BTB domain containing 4, Zinc finger and BTB domain-containing protein 4, ZNF903.

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Kr_ppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZBTB4 (zinc finger and BTB domain containing 4), also known as KAISO-L1 (KAISO-like zinc finger protein 1), is a 1,013 amino acid nuclear protein that is involved in transcriptional regulation. ZBTB4 contains one BTB (POZ) domain, six C2H2-type zinc fingers and is phosphorylated and downregulated by HIPK2. The gene encoding ZBTB4 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.

Gene ID: 57659