C4orf46 antibody (AA 51-113)

Catalog No. ABIN1713421

This Rabbit Polyclonal antibody specifically detects C4orf46 in ELISA, IF (cc), IF (p), IHC (fro), IHC (p) and ICC. It exhibits reactivity toward Human.

Quick Overview for C4orf46 antibody (AA 51-113) (ABIN1713421)

Target: C4orf46 (Chromosome 4 Open Reading Fram 46 (C4orf46))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This C4orf46 antibody is un-conjugated

Application: ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Product Details anti-C4orf46 Antibody

Binding Specificity: AA 51-113

Predicted Reactivity: Human,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human C4orf46

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for C4orf46

Target: C4orf46 (Chromosome 4 Open Reading Fram 46 (C4orf46))

Alternative Name: C4orf46

Background:

Synonyms: C4orf46, CD046_HUMAN, Chromosome 4 open reading frame 46, hypothetical protein LOC201725, Hypothetical protein LOC201725 2, Uncharacterized protein C4orf46.

Background: Representing approximately 6 % of the human genome, chromosome 4 contains nearly 900 genes. Notably, the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease, is on chromosome 4. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. Chromosome 4 reportedly contains the largest gene deserts (regions of the genome with no protein encoding genes) and has one of the two lowest recombination frequencies of the human chromosomes. The C4orf46 gene product has been provisionally designated C4orf46 pending further characterization.

Gene ID: 201725