EFTUD2 antibody (AA 901-972)

Catalog No. ABIN1714149

Product Details anti-EFTUD2 Antibody

Target: EFTUD2 (Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2))

Binding Specificity: AA 901-972

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EFTUD2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EFTUD2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for EFTUD2

Target: EFTUD2 (Elongation Factor Tu GTP Binding Domain Containing 2 (EFTUD2))

Alternative Name: EFTUD2 (EFTUD2 Products)

Synonyms: snrp116 antibody, snu114 antibody, wu:fi20f05 antibody, zgc:66214 antibody, U5-116KD antibody, SNRP116 antibody, MFDGA antibody, MFDM antibody, SNRNP116 antibody, Snrp116 antibody, Snu114 antibody, 116kDa antibody, U5-116kD antibody, elongation factor Tu GTP binding domain containing 2 S homeolog antibody, elongation factor Tu GTP binding domain containing 2 antibody, eftud2.S antibody, eftud2 antibody, EFTUD2 antibody, CpipJ_CPIJ011675 antibody, CpipJ_CPIJ016234 antibody, Eftud2 antibody

Background:

Synonyms: 116 kDa, 116 kDa U5 small nuclear ribonucleoprotein component, EFTUD2, Elongation factor Tu GTP binding domain containing 2, Elongation factor Tu GTP-binding domain-containing protein 2, hSNU114, MFDM, Snrp116, Snu114, SNU114 homolog, U5 116KD, U5 small nuclear ribonucleoprotein component, U5 snRNP specic protein, 116 kD, U5 snRNP specic protein, 116 kDa, U5 snRNP-specic protein, U5-116 kDa, U5S1_HUMAN.

Background: Spliceosomes are multi-protein complexes that are composed of snRNPs (small nuclear ribonucleoproteins) and a variety of associated protein factors, all of which work in concert to regulate the splicing of pre-mRNA. Snrp116, also known as EFTUD2 (elongation factor Tu GTP binding domain containing 2) or Snu114, is a 972 amino acid protein that localizes to the nucleus and belongs to the GTP-binding elongation factor family. Existing as a component of the multi-protein U5 snRNP spliceosome complex, Snrp116 plays an important role in pre-mRNA splicing, as well as in the recycling of spliceosomal snRNPs. The gene encoding Snrp116 maps to human chromosome 17, which comprises over 2.5 % of the human genome and encodes over 1,200 genes.

Gene ID: 9343