POLG antibody (AA 1101-1239)

Catalog No. ABIN1714946

The Rabbit Polyclonal anti-POLG antibody has been validated for WB, ELISA, ICC, IF (cc), IF (p), IHC (p) and IHC (fro). It is suitable to detect POLG in samples from Human, Mouse and Rat. There is 1 publication available.

Quick Overview for POLG antibody (AA 1101-1239) (ABIN1714946)

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLG antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-POLG Antibody

Binding Specificity: AA 1101-1239

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human POLG

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-POLG antibody (ABIN1714946)

Chen, Zhao, Cai, Sun, Hu, Huang, Kong, Kong: "The role of sodium hydrosulfide in attenuating the aging process via PI3K/AKT and CaMKKβ/AMPK pathways." in: Redox biology, Vol. 12, pp. 987-1003, (2017) (PubMed).

Target Details for POLG

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Alternative Name: DNA Polymerase gamma

Background:

Synonyms: PEO, MDP1, SCAE, MIRAS, POLG1, POLGA, SANDO, MTDPS4A, MTDPS4B, DNA polymerase subunit gamma-1, Mitochondrial DNA polymerase catalytic subunit, PolG-alpha, POLG

Background: Involved in the replication of mitochondrial DNA. Associates with mitochondrial DNA.

Gene ID: 5428

UniProt: P54098