POLG antibody (N-Term)

Catalog No. ABIN2783430

Product Details anti-POLG Antibody

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Horse, Saccharomyces cerevisiae, Zebrafish (Danio rerio), Dog, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This POLG antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: QDWQEQLVVG HNVSFDRAHI REQYLIQGSR MHFLDTMSMH MAISGLSSFQ

Predicted Reactivity: Cow: 100%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rat: 100%, Yeast: 79%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against Polg. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 1216 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-POLG antibody (ABIN2783430)

Mancini, Roncaglia, Brussino, Stevanin, Lo Buono, Krmac, Maltecca, Gazzano, Bartoletti Stella, Calvaruso, Iommarini, Cagnoli, Forlani, Le Ber, Durr, Brice, Ghigo, Casari, Porcelli, Funaro, Gasparre et al.: "Genome-wide expression profiling and functional characterization of SCA28 lymphoblastoid cell lines reveal impairment in cell growth and activation of apoptotic pathways. ..." in: BMC medical genomics, Vol. 6, pp. 22, (2013) (PubMed).

Target Details for POLG

Target: POLG (Polymerase (DNA Directed), gamma (POLG))

Alternative Name: Polg (POLG Products)

Synonyms: POLG antibody, MDP1 antibody, MIRAS antibody, MTDPS4A antibody, MTDPS4B antibody, PEO antibody, POLG1 antibody, POLGA antibody, SANDO antibody, SCAE antibody, AA409516 antibody, PolgA antibody, polymerase (DNA) gamma, catalytic subunit L homeolog antibody, DNA polymerase gamma, catalytic subunit antibody, polymerase (DNA directed), gamma antibody, polg.L antibody, Polg antibody, POLG antibody, polg antibody

Target Type: Viral Protein

Background: Polg is involved in the replication of mitochondrial DNA.
Alias Symbols: -
Protein Size: 1216

Molecular Weight: 136 kDa

Gene ID: 85472

NCBI Accession: NM_053528, NP_445980

UniProt: Q9QYV8