EPH Receptor B6 antibody (AA 601-750)

Catalog No. ABIN1724689

This Mouse Monoclonal antibody specifically detects EPH Receptor B6 in ELISA and IHC. It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for EPH Receptor B6 antibody (AA 601-750) (ABIN1724689)

Target: EPH Receptor B6 (EPHB6)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This EPH Receptor B6 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (IHC)

Clone: 2A6B9

Product Details anti-EPH Receptor B6 Antibody

Binding Specificity: AA 601-750

Purpose: EhpB6 Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of EphB6 (aa601-750) expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: ELISA: 1/10000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

References for anti-EPH Receptor B6 antibody (ABIN1724689)

Luo, Yu, Wu, Wu: "EphB6 crosslinking results in costimulation of T cells." in: The Journal of clinical investigation, Vol. 110, Issue 8, pp. 1141-50, (2002) (PubMed).

Target Details for EPH Receptor B6

Target: EPH Receptor B6 (EPHB6)

Background: EhpB6: EPH receptor B6. Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The ephrin receptor encoded by this gene lacks the kinase activity of most receptor tyrosine kinases and binds to ephrin-B ligands.

UniProt: O15197

Pathways: RTK Signaling, Hormone Transport