TP53BP1 antibody (AA 574-773)
Quick Overview for TP53BP1 antibody (AA 574-773) (ABIN1724820)
Target
See all TP53BP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- AA 574-773
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Purpose
- TP53BP1 Antibody
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Purification
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. Coli.
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Isotype
- IgG1
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Ascitic fluid containing 0.03 % sodium azide.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1." in: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012) (PubMed).
: "The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 9, pp. 1398-409, (2012) (PubMed).
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: "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1." in: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012) (PubMed).
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- TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
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Alternative Name
- TP53BP1
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Background
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T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis,enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage.
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Molecular Weight
- 213.6 kDa
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Gene ID
- 7158
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UniProt
- Q12888
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Pathways
- DNA Damage Repair
Target
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