TP53BP1 antibody (pSer1778)

Catalog No. ABIN6992435

Product Details anti-TP53BP1 Antibody

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Binding Specificity: pSer1778

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TP53BP1 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Anti-Phosphorylated Tumor Protein p53 Binding Protein 1 (TP53BP1) Monoclonal Antibody

Specificity: Phospho-TP53BP1 (Ser1778) antibody detects endogenous levels of TP53BP1 only when phosphorylated at serine 1778.

Purification: Protein A + Protein G affinity chromatography

Immunogen: Synthetic Phosphopeptide Phospho-TP53BP1 (Ser1778)

Clone: D4

Isotype: IgG

Application Details

Application Notes:

Western blotting: 0.5-5 μg/mL Immunocytochemistry in formalin fixed cells: 5-30 μg/mL Immunohistochemistry in formalin fixed frozen section: 5-30 μg/mL Immunohistochemistry in paraffin section: 5-30 μg/mL Enzyme-linked Immunosorbent Assay: 0.05-2 μg/mL Optimal working dilutions must be determined by end user.

Comment:

The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01M PBS, pH 7.4, containing 0.05 % Proclin-300, 50 % glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for frequent use. Stored at -20°C in a manual defrost freezer for two year without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Expiry Date: 24 months

Target Details for TP53BP1

Target: TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))

Alternative Name: Tumor Protein p53 Binding Protein 1 (TP53BP1 Products)

Synonyms: TP53BP1 antibody, MGC160112 antibody, 53BP1 antibody, Tp53bp1 antibody, m53BP1 antibody, p202 antibody, Trp53bp1 antibody, tumor protein p53 binding protein 1 antibody, tumor suppressor p53-binding protein 1 antibody, tumor protein p53 binding protein 1 (predicted), 5 prime antibody, transformation related protein 53 binding protein 1 antibody, TP53BP1 antibody, tp53bp1 antibody, LOC100550605 antibody, Trp53bp1 antibody, Tp53bp1 antibody

Background: 53BP1, p53BP1, p202

Pathways: DNA Damage Repair