TP53BP1 antibody (AA 574-773)
Quick Overview for TP53BP1 antibody (AA 574-773) (ABIN1724821)
Target
See all TP53BP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
 - AA 574-773
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Purpose
 - TP53BP1 Antibody
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Purification
 - Purified antibody
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Immunogen
 - Purified recombinant fragment of human TP53BP1 (AA: 574-773) expressed in E. Coli.
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Isotype
 - IgG1
 
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Application Notes
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ELISA: 1/10000
FCM: 1/200 - 1/400
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Restrictions
 - For Research Use only
 
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Format
 - Liquid
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Buffer
 - Purified antibody in PBS with 0.05 % sodium azide.
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Preservative
 - Sodium azide
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Precaution of Use
 - This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
 - 4 °C,-20 °C
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Storage Comment
 - Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
 
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                                            : "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1."    in: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012)         (PubMed).        
: "The in vivo dynamic interplay of MDC1 and 53BP1 at DNA damage-induced nuclear foci." in: The international journal of biochemistry & cell biology, Vol. 44, Issue 9, pp. 1398-409, (2012) (PubMed).
 
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                                            : "RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1."    in: Cancer research, Vol. 72, Issue 19, pp. 4974-83, (2012)         (PubMed).        
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- TP53BP1 (Tumor Protein P53 Binding Protein 1 (TP53BP1))
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Alternative Name
 - TP53BP1
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Background
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                        T protein p53 binding protein 1 may have a role in checkpoint signaling during mitosis,enhance TP53-mediated transcriptional activation and play a role in the response to DNA damage. 
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Molecular Weight
 - 213.6 kDa
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Gene ID
 - 7158
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UniProt
 - Q12888
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Pathways
 - DNA Damage Repair
 
Target
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