TEK antibody (Internal Region)

Catalog No. ABIN1732823

The Rabbit Polyclonal anti-TEK antibody has been validated for WB. It is suitable to detect TEK in samples from Human.

Quick Overview for TEK antibody (Internal Region) (ABIN1732823)

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TEK antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-TEK Antibody

Binding Specificity: AA 250-400, Internal Region

Specificity: Reacts with human ~150 kDa TEK protein

Purification: Purified

Immunogen: A genomic peptide made to an internal region of the human TIE2 protein (within residues 250-400).

Isotype: IgG

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
- WB : 1/2 500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS, glycerol 30 % , Sodium azide 0.05 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 6 months

Target Details for TEK

Target: TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Alternative Name: CD202b / Angiopoietin-1 Receptor

Background: The endothelium-specific receptor tyrosine kinase 2 binds and interacts with angiogenic proteins. In acute inflammation, TIE2 signals vascular endothelial cells to stop early leakiness in vessels. This interaction depends partly upon VEGF, PLGF and PDGF

UniProt: Q02763

Pathways: RTK Signaling, Growth Factor Binding