GPER antibody (AA 357-370)

Catalog No. ABIN1735055

The Goat Polyclonal anti-GPER antibody has been validated for IHC (p). It is suitable to detect GPER in samples from Human, Dog and Monkey.

Quick Overview for GPER antibody (AA 357-370) (ABIN1735055)

Target: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Reactivity: Human, Dog, Monkey

Host: Goat

Clonality: Polyclonal

Conjugate: This GPER antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-GPER Antibody

Binding Specificity: AA 357-370

Specificity: Reacts with GPR30 from human, gorilla, monkey and dogs

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Cross-Reactivity (Details): Predicted to cross reacts withmouse and rat protein (93 % immunogen sequences identity).

Purification: Antigen affinity purified

Immunogen: Synthetic peptide C-KAVIPDSTEQSDVR from positions 357-370 of human GPER (NP_001496.1). Percent identity with other species by BLAST analysis: Human, Monkey, Dog (100%), Mouse, Rat (93%)

Application Details

Application Notes:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IHC-P (3.75 - 7.5 μg/mL)

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: TBS, pH 7.3, BSA 0.5 % , Sodium azide 0.02 %

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Minimize freezing and thawing.

Target Details for GPER

Target: GPER (G Protein-Coupled Estrogen Receptor 1 (GPER))

Alternative Name: GPR30

Background: Involved in various biological pathways like immunity, apoptosis, cell cycle or differentiation, GPR30 is the eostradiol receptor for ER2

Gene ID: 2852

Pathways: EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process