PARK7/DJ1 antibody (C-Term)
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- Target See all PARK7/DJ1 (PARK7) Antibodies
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
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Binding Specificity
- AA 150-189, C-Term
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PARK7/DJ1 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Functional Studies (Func)
- Specificity
- Reacts with humanand mouse Protein DJ-1
- Cross-Reactivity
- Cow (Bovine), Chicken
- Cross-Reactivity (Details)
- May cross react with rat, bovine, Zebra fish, Golden hamster and chicken proteins (100 % sequence homology).
- Purification
- Antiserum
- Immunogen
- Synthetic peptide corresponding to the C-terminus (within residues 150-189) of human Park7(DJ-1).
- Top Product
- Discover our top product PARK7 Primary Antibody
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- Application Notes
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Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
ICC1:500 IP1:200 WB1:2 000 - Restrictions
- For Research Use only
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- Format
- Liquid
- Storage
- 4 °C/-20 °C
- Storage Comment
- Short term storage at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Expiry Date
- 6 months
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- Target
- PARK7/DJ1 (PARK7) (Parkinson Protein 7 (PARK7))
- Alternative Name
- Protein DJ-1 (PARK7 Products)
- Synonyms
- DJ-1 antibody, DJ1 antibody, CAP1 antibody, Dj1 antibody, SP22 antibody, dj1 antibody, zgc:103725 antibody, park7b antibody, park7 antibody, park7a antibody, Parkinsonism associated deglycase antibody, Parkinson disease (autosomal recessive, early onset) 7 antibody, parkinson protein 7 antibody, parkinson protein 7 S homeolog antibody, parkinson protein 7 L homeolog antibody, PARK7 antibody, Park7 antibody, park7 antibody, park7.S antibody, park7.L antibody
- Background
- Park7/DJ-1 is one of several genes thought to cause autosomal-recessive early-onset parkinsonism. Protects cells against oxidative stress and cell death. Plays a role in regulating expression or stability of the mitochondrial uncoupling proteins SLC25A14 and SLC25A27 in dopaminergic neurons of the substantia nigra pars compacta and attenuates the oxidative stress induced by calcium entry into the neurons via L-type channels during pacemaking. Eliminates hydrogen peroxide and protects cells against hydrogen peroxide-induced cell death.
- Gene ID
- 11315
- Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Proton Transport
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