GRIA2 antibody (AA 278-292)

Catalog No. ABIN1742378

The Mouse Monoclonal anti-GRIA2 antibody has been validated for WB and IP. It is suitable to detect GRIA2 in samples from Human, Rat and Mouse. There is 1 publication available.

Quick Overview for GRIA2 antibody (AA 278-292) (ABIN1742378)

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRIA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP)

Clone: 1404A10

Product Details anti-GRIA2 Antibody

Binding Specificity: AA 278-292

Purpose: Mouse anti-GluA2 IgG

Specificity: Specific for GluA 2.

Cross-Reactivity (Details): Reacts with: rat (P19491), mouse (P23819), human (P42262). No signal: zebrafish. Other species not tested yet.

Purification: purified IgG

Immunogen: Synthetic peptide corresponding to AA 278 to 292 from rat GluA2 (UniProt Id: P19491)

Isotype: IgG2b

Application Details

Application Notes: WB:1 : 1000

Comment:

IP:For most effective IP use the solubilization protocol described in this ELISA protocol. Consider that protein-protein interaction may be affected.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: For reconstitution add 100 μLH2O to get a 1 mg/mL solution in PBS.

Buffer: PBS. Albumin and azide were added for stabilization.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze! Antibodies should be stored at +4°C when still lyophilized.

Storage: -20 °C,-80 °C,4 °C

Storage Comment: Antibodies should be stored at +4°C when still lyophilized. Then aliquot and store at -20°C to -80°C until use. Albumin and azide were added for stabilization. Do not freeze!

References for anti-GRIA2 antibody (ABIN1742378)

Jedlicka, Vnencak, Krueger, Jungenitz, Brose, Schwarzacher: "Neuroligin-1 regulates excitatory synaptic transmission, LTP and EPSP-spike coupling in the dentate gyrus in vivo." in: Brain structure & function, Vol. 220, Issue 1, pp. 47-58, (2015) (PubMed).

Target Details for GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Alternative Name: GluA2

Background:

Synonyms: AMPA 2, GluR2, glutamate receptor, AMPAR, AMPA receptor

Antigen Information: GluAs are ionotropic glutamate receptors involved in rapid excitatory neurotransmission

UniProt: P19491

Pathways: PI3K-Akt Signaling