Cardiac Troponin T2 antibody

Catalog No. ABIN180977

The Mouse Monoclonal anti-Cardiac Troponin T2 antibody is suitable to detect Cardiac Troponin T2 in samples from Human. It has been validated for WB and EIA.

Quick Overview for Cardiac Troponin T2 antibody (ABIN180977)

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Cardiac Troponin T2 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: BGN-1288-44

Product Details anti-Cardiac Troponin T2 Antibody

Specificity: This antibody recognizes Troponin T Cardiac Isoform 1. Under reducing conditions, this antibody reacts with purified cardiac isoform in Western blotting and does not react with the skeletal isoform under the same conditions.

Characteristics: Synonyms: cTnT, TnTc, TNNT2

Purification: Affinity Chromatography on Protein A

Immunogen: HMW conjugateAA Sequence: F-M-P-N-L-V-P-P-K-I-C

Isotype: IgG1

Application Details

Application Notes: ELISA. Western Blot: Reacts with reduced purified cardiac isoform in Western blotting at a titre ofgreater than 1/250. Does not react with the skeletal isoform under the same conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: PBS, pH 7.2, 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Expiry Date: 12 months

Target Details for Cardiac Troponin T2

Target: Cardiac Troponin T2 (cTnT) (Cardiac Troponin T (cTnT))

Alternative Name: Cardiac Troponin T

Background: Cardiac Troponin T, a 36 kDa protein, is the tropomyosin binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations within the protein have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for the gene undergo alternative splicing that results in many tissue specific isoforms.Synonyms: TNNT2, TnTc, cTnT

Gene ID: 7139

UniProt: P45379