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CD11b antibody

ITGAM Reactivity: Rat IHC, IHC (fro) Host: Mouse Monoclonal ED8 unconjugated
Catalog No. ABIN1820242
  • Target See all CD11b (ITGAM) Antibodies
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Reactivity
    • 239
    • 168
    • 63
    • 30
    • 17
    • 17
    • 16
    • 14
    • 9
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Rat
    Host
    • 135
    • 106
    • 98
    • 1
    • 1
    Mouse
    Clonality
    • 254
    • 83
    • 2
    Monoclonal
    Conjugate
    • 110
    • 38
    • 26
    • 24
    • 18
    • 9
    • 7
    • 7
    • 5
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    • 5
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    • 4
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    • 3
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    • 3
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    • 3
    • 3
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    • 3
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    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD11b antibody is un-conjugated
    Application
    • 258
    • 80
    • 76
    • 74
    • 56
    • 42
    • 34
    • 23
    • 23
    • 15
    • 12
    • 12
    • 8
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    • 3
    • 2
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    • 1
    • 1
    Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificity
    Recognizes a membrane antigen on rat macrophages, monocytes, dendritic cells and granulocytes. It also recognizes small ramified microglia in the central nervous system. No other cell types are positive for ED8. The recognized antigen is a heterodimer (160 and 95kD) belonging to the family of adhesion molecules CD11b/CD18, also designated as Mac-1 antigen or CR3. ED7 and ED8 may recognize closely related epitopes on the same molecule. ED7 and ED8 have been shown to induce homotypic aggregation of granulocytes.
    Purification
    Protein G purified
    Immunogen
    Rat spleen cell homogenate with FCA.
    Clone
    ED8
    Isotype
    IgG1
    Top Product
    Discover our top product ITGAM Primary Antibody
  • Application Notes
    Approved: IHC, IHC-Fr

    Not recommended for: IHC-P
    Comment

    Target Species of Antibody: Rat

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    4°C or -20°C, Avoid freeze-thaw cycles.
  • Target
    CD11b (ITGAM) (Integrin alpha M (ITGAM))
    Alternative Name
    ITGAM / CD11b (ITGAM Products)
    Background
    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain
    Gene ID
    3684
    Pathways
    Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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