Integrin Alpha2b antibody (AA 45-149)

Catalog No. ABIN1844101

Product Details anti-Integrin Alpha2b Antibody

Target: Integrin Alpha2b (CD41)

Binding Specificity: AA 45-149

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Integrin Alpha2b antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human ITGA2B (AA: 45-149) expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for Integrin Alpha2b

Target: Integrin Alpha2b (CD41)

Alternative Name: ITGA2B (CD41 Products)

Background: ITGA2B encodes integrin alpha chain 2b.Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain.Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation.Mutations that interfere with this role result in thrombasthenia.In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Molecular Weight: 113.4 kDa

Gene ID: 3674

UniProt: P08514

Pathways: Integrin Complex