EGFR Mutant (AA 693-893), (Mutant) antibody
Reactivity: Human
IHC, ELISA, WB, FACS
Host: Mouse
Monoclonal
unconjugated
-
- Target
- EGFR Mutant
- Binding Specificity
- AA 693-893, Mutant
- Reactivity
- Human
- Host
- Mouse
- Clonality
- Monoclonal
- Application
- Immunohistochemistry (IHC), ELISA, Western Blotting (WB), Flow Cytometry (FACS)
- Purification
- Purified antibody
- Immunogen
- Purified recombinant fragment of human EGFR mutant (AA: 693-893) expressed in E. coli.
- Isotype
- IgG1
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
-
- Target
- EGFR Mutant
- Background
- The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily.This protein is a receptor for members of the epidermal growth factor family.EGFR is a cell surface protein that binds to epidermal growth factor.Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation.Mutations in this gene are associated with lung cancer.Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
- Molecular Weight
- 175 kDa
- Gene ID
- 1956
- UniProt
- P00533
-
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