TNNI2 antibody

Catalog No. ABIN1845958

Product Details anti-TNNI2 Antibody

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNNI2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (fixed cells) (IF/ICC), Flow Cytometry (FACS)

Purification: Purified antibody

Immunogen: Purified recombinant fragment of human TNNI2 expressed in E. coli.

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: PBS with 0.05 % sodium azide and 0.5 % protein stabilizer.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.

Target Details for TNNI2

Target: TNNI2 (Fast Skeletal Troponin I (TNNI2))

Alternative Name: TNNI2 (TNNI2 Products)

Synonyms: AMCD2B antibody, DA2B antibody, FSSV antibody, fsTnI antibody, TnI-F4 antibody, TnI antibody, TNI antibody, hm:zehn0173 antibody, tnni2 antibody, tropI-1d antibody, zgc:86800 antibody, troponin I2, fast skeletal type antibody, troponin I type 2 (skeletal, fast) antibody, troponin I, fast skeletal muscle-like antibody, troponin I, skeletal, fast 2 antibody, troponin I type 2a (skeletal, fast), tandem duplicate 4 antibody, TNNI2 antibody, Tnni2 antibody, tnni2a.4 antibody

Background: This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits.The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction.Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function.In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha.This protein also suppresses tumor growth in human ovarian carcinoma.Mutations in this gene cause myopathy and distal arthrogryposis type 2B.Alternatively spliced transcript variants have been found for this gene.

Molecular Weight: 21 kDa

Gene ID: 7136

UniProt: P48788