ITPR3 antibody (Internal Region)

Catalog No. ABIN185541

The Goat Polyclonal anti-ITPR3 antibody (ABIN185541) specifically detects ITPR3 in ELISA. The antibody is reactive with Human samples.

Quick Overview for ITPR3 antibody (Internal Region) (ABIN185541)

Target: ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This ITPR3 antibody is un-conjugated

Application: ELISA

Grade: Recent

Product Details anti-ITPR3 Antibody

Binding Specificity: Internal Region

Purpose: ITPR3

Sequence: DKKERPTDEE GFLH

Specificity: No cross-reactivity expected with other types of ITPR

Cross-Reactivity: Cow, Dog, Human, Mouse, Rat

Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.

Immunogen: Peptide with sequence C-DKKERPTDEEGFLH, from the internal region of the protein sequence according to NP_002215.2.

Isotype: IgG

Application Details

Application Notes:

Western Blot: Preliminary experiments gave an approx 60 kDa band in Human Adipose, Colon, Duodenum, Heart and Liver lysates after 1 μg/mL antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe

Peptide ELISA: antibody detection limit dilution 1:128000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Supplied at 0.5 mg/mL in Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Minimize freezing and thawing.

Storage: -20 °C

Storage Comment: Aliquot and store at -20°C, with minimal freeze/thawing. A working aliquot may be refrigerated at 4°C for a few weeks and still remain viable.

Target Details for ITPR3

Target: ITPR3 (Inositol 1,4,5-Trisphosphate Receptor, Type 3 (ITPR3))

Alternative Name: ITPR3

Background: ITPR3, inositol 1,4,5-triphosphate receptor, type 3 , HGNC:6182, FLJ36205, IP3R, IP3R3

Gene ID: 3710

NCBI Accession: NP_002215

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma, BCR Signaling