PSMB2 antibody (C-Term)

Catalog No. ABIN1881696

Cited in 3+ publications. The Rabbit Polyclonal anti-PSMB2 antibody (ABIN1881696) specifically detects PSMB2 in WB and IHC (p). The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for PSMB2 antibody (C-Term) (ABIN1881696)

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-PSMB2 Antibody

Binding Specificity: AA 133-163, C-Term

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PSMB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-163 amino acids from the C-terminal region of human PSMB2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:25

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-PSMB2 antibody (ABIN1881696)

Apcher, Heink, Zantopf, Kloetzel, Schmid, Mayer, Krüger: "Human immunodeficiency virus-1 Tat protein interacts with distinct proteasomal alpha and beta subunits." in: FEBS letters, Vol. 553, Issue 1-2, pp. 200-4, (2003) (PubMed).

Kristensen, Johnsen, Uerkvitz, Tanaka, Hendil: "Human proteasome subunits from 2-dimensional gels identified by partial sequencing." in: Biochemical and biophysical research communications, Vol. 205, Issue 3, pp. 1785-9, (1995) (PubMed).

Nothwang, Tamura, Tanaka, Ichihara: "Sequence analyses and inter-species comparisons of three novel human proteasomal subunits, HsN3, HsC7-I and HsC10-II, confine potential proteolytic active-site residues." in: Biochimica et biophysica acta, Vol. 1219, Issue 2, pp. 361-8, (1994) (PubMed).

Target Details for PSMB2

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Alternative Name: PSMB2

Background: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH . The proteasome has an ATP-dependent proteolytic activity. This subunit has a trypsin-like activity.

Molecular Weight: 22836

NCBI Accession: NP_002785

UniProt: P49721

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA