PSMB2 antibody (AA 151-201)

Catalog No. ABIN7453444

Product Details anti-PSMB2 Antibody

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Binding Specificity: AA 151-201

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMB2 antibody is un-conjugated

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Purpose: Rabbit anti-PSMB2 Antibody, Affinity Purified

Predicted Reactivity: Bovine

Purification: Affinity Purified

Immunogen: Between AA 151 and 201

Isotype: IgG

Application Details

Application Notes:

IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

IP: 2 - 10 μg/mg lysate

WB: 1:2,000 - 1:10,000

Restrictions: For Research Use only

Handling

Concentration: 1000 μg/mL

Buffer: Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Expiry Date: 12 months

Target Details for PSMB2

Target: PSMB2 (Proteasome (Prosome, Macropain) Subunit, beta Type 2 (PSMB2))

Alternative Name: PSMB2 (PSMB2 Products)

Synonyms: HC7-I antibody, 19.m02268 antibody, DDBDRAFT_0190287 antibody, DDBDRAFT_0232958 antibody, DDB_0190287 antibody, DDB_0232958 antibody, Psmb2 antibody, ACYPI004276 antibody, AU045357 antibody, AW108089 antibody, C7-I antibody, D4Wsu33e antibody, zgc:92282 antibody, proteasome subunit beta 2 antibody, proteasome subunit beta type 2 antibody, proteasome beta 2 subunit antibody, putative proteasome beta 2 subunit antibody, 20S proteasome subunit beta-2 antibody, proteasome (prosome, macropain) subunit, beta type 2 antibody, proteasome subunit beta 2 L homeolog antibody, PSMB2 antibody, CNC04990 antibody, Tc00.1047053510287.30 antibody, Tc00.1047053503891.100 antibody, Tc00.1047053508461.430 antibody, LBRM_34_3820 antibody, LBRM_35_0400 antibody, BBOV_I004450 antibody, LMJF_36_0320 antibody, psmB2 antibody, Psmb2 antibody, psmb2 antibody, psmb2.L antibody

Background: Background: Proteasome (prosome, macropain) subunit, alpha type, 2 (PSMA2) is a component of the proteasome, a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA2 is a member of the peptidase T1A family, that is a 20S core alpha subunit [taken from NCBI Entrez Gene (Gene ID: 5683)].

Gene ID: 5690

NCBI Accession: NP_002785

UniProt: P49721

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA