AIM2 antibody

Catalog No. ABIN1882191

This anti-AIM2 antibody is a Mouse Monoclonal antibody detecting AIM2 in WB. Suitable for Human. This Primary Antibody has been cited in 3+ publications.

Quick Overview for AIM2 antibody (ABIN1882191)

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This AIM2 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 812CT9-2-2-1

Product Details anti-AIM2 Antibody

Purification: This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

Immunogen: This AIM2 Monoclonal antibody is generated from mouses immunized with a KLH conjugated synthetic peptide selected from the 10-40 region of human AIM2.

Isotype: IgM

Application Details

Application Notes: WB: 1:1000. WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Expiry Date: 6 months

References for anti-AIM2 antibody (ABIN1882191)

Chen, Ou-Yang, Hung, Liu, Wang, Wang, Hou, Hortobagyi, Hung: "AIM2 suppresses human breast cancer cell proliferation in vitro and mammary tumor growth in a mouse model." in: Molecular cancer therapeutics, Vol. 5, Issue 1, pp. 1-7, (2006) (PubMed).

Cresswell, Clarke, Jackson, Darcy, Trapani, Johnstone: "Biochemical and growth regulatory activities of the HIN-200 family member and putative tumor suppressor protein, AIM2." in: Biochemical and biophysical research communications, Vol. 326, Issue 2, pp. 417-24, (2004) (PubMed).

DeYoung, Ray, Su, Anzick, Johnstone, Trapani, Meltzer, Trent: "Cloning a novel member of the human interferon-inducible gene family associated with control of tumorigenicity in a model of human melanoma." in: Oncogene, Vol. 15, Issue 4, pp. 453-7, (1997) (PubMed).

Target Details for AIM2

Target: AIM2 (Absent in Melanoma 2 (AIM2))

Alternative Name: AIM2

Background: Tumor suppressor which may act by repressing NF-kappa-B transcriptional activity.

Molecular Weight: 38954

NCBI Accession: NP_004824

UniProt: O14862

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome