H2AFZ antibody (AA 1-15)

Catalog No. ABIN1885636

This Rabbit Polyclonal antibody specifically detects H2AFZ in WB, IHC and IF. It exhibits reactivity toward Human.

Quick Overview for H2AFZ antibody (AA 1-15) (ABIN1885636)

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This H2AFZ antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-H2AFZ Antibody

Binding Specificity: AA 1-15

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 1 and 15 of Human H2AFZ

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for H2AFZ

Target: H2AFZ (H2A Histone Family, Member Z (H2AFZ))

Alternative Name: Histone H2A.Z/H2A.F/Z

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes.Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4).The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family.Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.[provided by RefSeq]
Synonyms: H2AZ, H2A.z, H2A/z, MGC117173

Molecular Weight: 14 kDa

Gene ID: 3015

NCBI Accession: NM_002106, NP_002097

Pathways: Telomere Maintenance