RACGAP1 antibody (AA 1-172)
Quick Overview for RACGAP1 antibody (AA 1-172) (ABIN1885689)
Target
See all RACGAP1 AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-172
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Purification
- Purified by antigen-affinity chromatography.
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Immunogen
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 172 of RACGAP1
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Application Notes
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Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200 -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
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Preservative
- Thimerosal (Merthiolate)
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Precaution of Use
- Biohazard Informations: This product contains thimerosal which is hazardous.
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Storage
- 4 °C/-20 °C
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Storage Comment
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
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Alternative Name
- RACGAP1
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Background
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Rho GTPases control a variety of cellular processes.There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370), RAC (see RAC1, MIM 602048), and CDC42 (MIM 116952).GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis.Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals.GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.[supplied by OMIM]
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Molecular Weight
- 71 kDa
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Gene ID
- 29127
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Pathways
- Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
Target
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