FANCA antibody (AA 1-190)

Catalog No. ABIN1885743

The Rabbit Polyclonal anti-FANCA antibody (ABIN1885743) specifically detects FANCA in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for FANCA antibody (AA 1-190) (ABIN1885743)

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This FANCA antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-FANCA Antibody

Binding Specificity: AA 1-190

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 190 of FACA

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for FANCA

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Alternative Name: FACA

Background: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2).The previously defined group FANCH is the same as FANCA.Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair.The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex.This gene encodes the protein for complementation group A.Alternative splicing results in multiple transcript variants encoding different isoforms.Mutations in this gene are the most common cause of Fanconi anemia.[provided by RefSeq]

Molecular Weight: 33 kDa

Gene ID: 2175

Pathways: DNA Damage Repair