MGC64314 antibody, zeh1094 antibody, zgc:85649 antibody, hm:zeh1094 antibody, wu:fa96a09 antibody, wu:fj39g07 antibody, HTF9A antibody, Htf9a antibody, RAN binding protein 1 S homeolog antibody, RAN binding protein 1 L homeolog antibody, ran binding protein 1 antibody, RAN binding protein 1 antibody, ran-specific GTPase-activating protein pseudogene antibody, ranbp1.S antibody, ranbp1.L antibody, PVX_090070 antibody, GL50803_16969 antibody, LOC100343953 antibody, ranbp1 antibody, RANBP1 antibody, Ranbp1 antibody
Background
Ran/TC4-binding protein, RanBP1, interacts specifically with GTP-charged RAN.RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP.RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1).The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog.In both mammalian cells and in yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.[provided by RefSeq]