Prosaposin antibody (AA 1-220)

Catalog No. ABIN1885798

This Rabbit Polyclonal antibody specifically detects Prosaposin in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for Prosaposin antibody (AA 1-220) (ABIN1885798)

Target: Prosaposin (PSAP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prosaposin antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-Prosaposin Antibody

Binding Specificity: AA 1-220

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 220 of PSAP

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.50-1.500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Prosaposin

Target: Prosaposin (PSAP)

Alternative Name: PSAP

Background: This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D.Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites.Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups.The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy.Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq]

Molecular Weight: 58 kDa

Gene ID: 5660

NCBI Accession: NP_002769, NM_002778

Pathways: Positive Regulation of Endopeptidase Activity