Endothelin 1 antibody (AA 141-203)

Catalog No. ABIN1886037

The Rabbit Polyclonal anti-Endothelin 1 antibody (ABIN1886037) specifically detects Endothelin 1 in WB and IF. The antibody is reactive with Human samples.

Quick Overview for Endothelin 1 antibody (AA 141-203) (ABIN1886037)

Target: Endothelin 1 (EDN1)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Endothelin 1 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF)

Product Details anti-Endothelin 1 Antibody

Binding Specificity: AA 141-203

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 141 and 203 of Human EDN1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 20 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for Endothelin 1

Target: Endothelin 1 (EDN1)

Alternative Name: Endothelin 1

Background: The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1.This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells.Endothelin 1 also can affect the central nervous system.Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq]

Molecular Weight: 24 kDa

Gene ID: 1906

NCBI Accession: NP_001946, NM_001955

Pathways: Hormone Transport, Negative Regulation of Hormone Secretion, Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Cell Size