ORC2 antibody (AA 208-449)

Catalog No. ABIN1886184

The Rabbit Polyclonal anti-ORC2 antibody (ABIN1886184) specifically detects ORC2 in WB and IHC. The antibody is reactive with Human samples.

Quick Overview for ORC2 antibody (AA 208-449) (ABIN1886184)

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ORC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-ORC2 Antibody

Binding Specificity: AA 208-449

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 208 and 449 of ORC2

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for ORC2

Target: ORC2 (Origin Recognition Complex Subunit 2 (ORC2))

Alternative Name: ORC2

Background: The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells.Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins.The protein encoded by this gene is a subunit of the ORC complex.This protein forms a core complex with ORC3L, -4L, and -5L.It also interacts with CDC45L and MCM10, which are proteins known to be important for the initiation of DNA replication.This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication.[provided by RefSeq]

Molecular Weight: 66 kDa

Gene ID: 4999

NCBI Accession: NM_006190, NP_006181