NQO1 antibody (AA 213-274)

Catalog No. ABIN1886199

The Rabbit Polyclonal anti-NQO1 antibody (ABIN1886199) specifically detects NQO1 in WB, IHC and IF. The antibody is reactive with Human samples.

Quick Overview for NQO1 antibody (AA 213-274) (ABIN1886199)

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NQO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-NQO1 Antibody

Binding Specificity: AA 213-274

Purification: Purified by antigen-affinity chromatography.

Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 213 and 274 of NQO1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.500
Immunofluorescence: 1.100-1.200

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for NQO1

Target: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Alternative Name: NQO1

Background: This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase.This FAD-binding protein forms homodimers and reduces quinones to hydroquinones.This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species.Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer.Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD).Alternate transcriptional splice variants, encoding different isoforms, have been characterized.[provided by RefSeq]

Molecular Weight: 31 kDa

Gene ID: 1728

NCBI Accession: NM_000903, NP_000894