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Chitotriosidase 1 antibody (AA 216-433)
CHIT1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-Chitotriosidase 1 Antibody
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Target
See all Chitotriosidase 1 (CHIT1) Antibodies
Chitotriosidase 1 (CHIT1)
(Chitotriosidase (CHIT1))
Binding Specificity
All epitopes for Chitotriosidase 1 antibodies
AA 216-433
Reactivity
All reactivities for Chitotriosidase 1 antibodies
Human
Host
All hosts for Chitotriosidase 1 antibodies
Rabbit
Clonality
All clonalities for Chitotriosidase 1 antibodies
Polyclonal
Conjugate
All conjugates for Chitotriosidase 1 antibodies
This Chitotriosidase 1 antibody is un-conjugated
Application
All applications for Chitotriosidase 1 antibodies
Western Blotting (WB)
Purification
Purified by antigen-affinity chromatography.
Immunogen
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 216 and 433 of Chitotriosidase
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Alternatives
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Application Details
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Application Notes
Suggested dilutions: Western blotting: 1.500-1.3000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.
Preservative
Thimerosal (Merthiolate)
Precaution of Use
Biohazard Informations: This product contains thimerosal which is hazardous.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for Chitotriosidase 1
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Target
Chitotriosidase 1 (CHIT1)
(Chitotriosidase (CHIT1))
Alternative Name
Chitotriosidase (CHIT1 Products )
Synonyms
CHI3 antibody, CHIT antibody, CHITD antibody, CHIT1 antibody, chio antibody, 2300002L19Rik antibody, chitinase 1 antibody, chitinase 1 (chitotriosidase) antibody, CHIT1 antibody, chit1 antibody, Chit1 antibody
Background
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients.The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture.Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression.This enzyme may play a role in the degradation of chitin-containing pathogens.[provided by RefSeq]
Molecular Weight
52 kDa
Gene ID
1118
NCBI Accession
NM_003465 , NP_003456
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