SSRP1 antibody (AA 75-308)

Catalog No. ABIN1886647

This Rabbit Polyclonal antibody specifically detects SSRP1 in WB and IHC. It exhibits reactivity toward Human.

Quick Overview for SSRP1 antibody (AA 75-308) (ABIN1886647)

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSRP1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-SSRP1 Antibody

Binding Specificity: AA 75-308

Purification: Purified by antigen-affinity chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 75 and 308 of SSRP1

Application Details

Application Notes: Suggested dilutions:
Western blotting: 1.500-1.3000
Immunohistochemistry: 1.100-1.250

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.1 M Tris-buffered saline with 10 % Glycerol (pH 7.0).0.01 % Thimerosal was added as a preservative.

Preservative: Thimerosal (Merthiolate)

Precaution of Use: Biohazard Informations: This product contains thimerosal which is hazardous.

Storage: 4 °C/-20 °C

Storage Comment: Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.

Target Details for SSRP1

Target: SSRP1 (Structure Specific Recognition Protein 1 (SSRP1))

Alternative Name: SSRP1

Background: The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT.FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation.FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin.This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA.This protein also functions as a co-activator of the transcriptional activator p63.An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known.[provided by RefSeq]

Molecular Weight: 81 kDa

Gene ID: 6749

NCBI Accession: NM_003146, NP_003137

Pathways: Chromatin Binding