PPAPDC1A antibody (C-Term)

Catalog No. ABIN1886984

Product Details anti-PPAPDC1A Antibody

Target: PPAPDC1A (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1A (PPAPDC1A))

Binding Specificity: C-Term

Reactivity: Mouse, Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PPAPDC1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purification: Affinity chromatography purified via peptide column

Immunogen: 14 amino acid peptide near the carboxy terminus of human PPAPDC1A.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for PPAPDC1A

Target: PPAPDC1A (Phosphatidic Acid Phosphatase Type 2 Domain Containing 1A (PPAPDC1A))

Alternative Name: PPAPDC1A (PPAPDC1A Products)

Synonyms: PPAPDC1A antibody, PPAPDC1 antibody, DPPL2 antibody, C030048B12Rik antibody, Gm1090 antibody, RGD1306289 antibody, phospholipid phosphatase 4 antibody, phospholipid phosphatase 4 L homeolog antibody, PLPP4 antibody, plpp4.L antibody, Plpp4 antibody

Background: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells.Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+.A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated.PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate.PPAPDC1A is preferentially expressed in endothelial cells.Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.
Synonyms: DPPL2, phosphatidic acid phosphatase type 2 domain containing 1, PPAPDC1

NCBI Accession: NP_001025230