Leucine Rich Repeat and Fibronectin Type III Domain Containing 4 (LRFN4) (C-Term) antibody

Details for Product No. ABIN1886999
Target
Binding Specificity
C-Term
5
Reactivity
Human, Mouse, Rat
6
4
4
Host
Rabbit
7
Clonality
Polyclonal
Application
Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
7
5
5
1
1
1
1
Options
Immunogen 14amino acid peptide near the carboxy terminus of human LRFN4.
Cross-Reactivity (Details) This antibody is predicted to not cross-react with other members of the LRFN family.
Purification Affinity chromatography purified via peptide column
Target
Alternative Name LRFN4 (LRFN4 Antibody Abstract)
Background LRFN4 is one of a family of five transmembrane glycoproteins that are highly expressed in neuronal tissues.LRFN proteins share leucine-rich repeat (LRR)-immunoglobulin-like (Ig)-fibronectin type III (Fn)-transmembrane domain structure with other members of the LRR-Ig-Fn protein superfamily such as the Slitrk family of proteins.Expression of LRFN1, -3, and -4 mRNA was detected in embryonic neuronal cells, while Lrfn2 and Lrfn5 expression was primarily restricted to more mature cells.LRFN1, -2, and -4 bound to PDZ domains of postsynaptic PSD95, re-distributing PSD95 to the cell periphery.It has been suggested that the Lrfn proteins play a role in the developing and/or mature vertebrate nervous system.At least two isoforms of LRFN4 are known to exist.
Synonyms: Leucine-rich repeat and fibronectin typeIII domain-containing protein 4, synaptic adhesion-like molecule 3, SALM3, FIGLER6
UniProt Q6PJG9
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02 % sodium azide.
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freezing and thawing repeatly.
Storage 4 °C/-20 °C
Storage Comment Store at 4 °C for short term use.Store at -20 °C for long term preservation.