Ly6k antibody (N-Term)

Catalog No. ABIN1888169

Product Details anti-Ly6k Antibody

Target: Ly6k (Lymphocyte Antigen 6 Complex, Locus K (Ly6k))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Ly6k antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Specificity: Multiple isoforms of LY6K are known to exist.

Purification: Affinity chromatography purified via peptide column

Immunogen: LY6K antibody was raised against an 18 amino acid peptide near the amino terminus of human LY6K.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handling Advice: Avoid freezing and thawing repeatly.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Target Details for Ly6k

Target: Ly6k (Lymphocyte Antigen 6 Complex, Locus K (Ly6k))

Alternative Name: LY6K (Ly6k Products)

Synonyms: LY6K antibody, CT97 antibody, HSJ001348 antibody, ly-6K antibody, 2410015A16Rik antibody, 3110035B01Rik antibody, mLy-6K antibody, lymphocyte antigen 6 family member K antibody, lymphocyte antigen 6 complex, locus K antibody, LY6K antibody, Ly6k antibody

Background: The lymphocyte antigen 6 complex locus K (LY6K), a member of cancer-testis antigen was initially identified as a molecular marker for head-and-neck squamous cell carcinoma as well a breast cancer.LY6K is a GPI-anchored membrane protein that is specifically associated with germ cell marker TEX101 and is strongly observed in testis, but only weakly in other tissues.LY6K mRNA was found to be upregulated in numerous bladder cancers due to gene amplification.Furthermore, knockdown experiments using LY6K siRNA reduced cell growth, migration and invasion in bladder carcinoma cell lines, suggesting that LY6K contributes to bladder cancer development.
Synonyms: Lymphocyte antigen 6 complex locus K, ly-6K, CT97