Lamin A/C antibody (AA 550-600)

Catalog No. ABIN1910113

This Rabbit Polyclonal antibody specifically detects Lamin A/C in WB, IHC, IF, IP and IHC (p). It exhibits reactivity toward Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Horse and Guinea Pig.

Quick Overview for Lamin A/C antibody (AA 550-600) (ABIN1910113)

Target: Lamin A/C (LMNA)

Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Rabbit, Horse, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Lamin A/C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-Lamin A/C Antibody

Binding Specificity: AA 550-600

Specificity: Region between residue 550 and 600 of human Lamin A using the numbering given in entry NP_733821.1 (GeneID 4000).

Purification: Immunoaffinity purified

Isotype: IgG

Application Details

Application Notes: Approved: IF (1:100 - 1:500), IHC, IHC-P (1:200 - 1:1000), IP (2 - 10 μg/mg lysate), WB (1:2000 - 1:10000)

Usage: Immunohistochemistry: Antigen retrieval with citrate buffer  pH 6.0 is recommended for FFPE tissue sections. Human controls: Breast Carcinoma, Colon Carcinoma, Linitis Plastica Stomach Cancer, Osteosarcoma, Ovarian Carcinoma, Stomach Adenocarcinoma, Testicular Seminoma.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline, 0.1 % BSA, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2-8°C for up to 1 year.

Expiry Date: 12 months

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: LMNA / Lamin A/C

Background: Name/Gene ID: LMNA

Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1

This antibody detects: LMNA / Lamin A+C

Gene ID: 4000

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus