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GRIA2 antibody (Ser880)

The Rabbit Polyclonal anti-GRIA2 antibody is suitable to detect GRIA2 in samples from Human and Mouse. It has been validated for WB.
Catalog No. ABIN197558
$588.00
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Quick Overview for GRIA2 antibody (Ser880) (ABIN197558)

Target

See all GRIA2 Antibodies
GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Reactivity

  • 102
  • 85
  • 70
  • 10
  • 8
  • 8
  • 6
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 1
  • 1
Human, Mouse

Host

  • 99
  • 19
  • 1
Rabbit

Clonality

  • 78
  • 41
Polyclonal

Conjugate

  • 60
  • 6
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GRIA2 antibody is un-conjugated

Application

  • 95
  • 37
  • 30
  • 27
  • 27
  • 27
  • 25
  • 23
  • 17
  • 13
  • 7
  • 3
  • 3
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB)
  • Binding Specificity

    • 29
    • 16
    • 13
    • 8
    • 7
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser880

    Specificity

    Glutamate receptor 2 (Precursor) antibody detects endogenous levels of total Glutamate receptor 2(Precursor) protein.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogen

    The antiserum was produced against synthesized non-phosphopeptide derived from human Glutamate receptor 2(Precursor) around the phosphorylation site of serine 880 (I-E- SP-V-K).
  • Application Notes

    Western Blot: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS (without Mg2+ and Ca2+), pH 7.4 containing 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Handling Advice

    Avoid repeated freezing and thawing.

    Storage

    -20 °C
  • Target

    GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

    Alternative Name

    Glutamate Receptor 2 / GLUR2

    Background

    Glutamate receptors sensitive to AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate) are ligand-activated cation channels that mediate the fast component of excitatory postsynaptic currents in neurons of the central nervous system. These channels are assembled from 4 related subunits, GLURA (GRIA1), GLURB (GRIA2), GLURC (GRIA3), GLURD (GRIA4), with the GLURB subunit rendering the channel almost impermeable to Ca(2+).Synonyms: AMPA-selective glutamate receptor 2, AMPA2, GRIA2, GluR-B, GluR-K2, Glutamate receptor ionotropic

    Gene ID

    2891

    NCBI Accession

    NP_000817

    UniProt

    P42262

    Pathways

    PI3K-Akt Signaling
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