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CHEK1 antibody (AA 250-300)

This Rabbit Polyclonal antibody specifically detects CHEK1 in IHC, IF and IHC (p). It exhibits reactivity toward Human, Mouse, Dog and Pig.
Catalog No. ABIN1977790

Quick Overview for CHEK1 antibody (AA 250-300) (ABIN1977790)

Target

See all CHEK1 Antibodies
CHEK1 (Checkpoint Kinase 1 (CHEK1))

Reactivity

  • 177
  • 113
  • 62
  • 16
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Human, Mouse, Dog, Pig

Host

  • 193
  • 12
  • 5
  • 5
Rabbit

Clonality

  • 188
  • 28
Polyclonal

Conjugate

  • 122
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  • 4
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  • 3
This CHEK1 antibody is un-conjugated

Application

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  • 32
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Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Binding Specificity

    • 36
    • 28
    • 19
    • 16
    • 9
    • 7
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    AA 250-300

    Specificity

    Region between residue 250 and 300 of human Checkpoint Kinase 1 using the numbering given in SwissProt entry O14757 (GeneID 1111).

    Purification

    Immunoaffinity purified

    Isotype

    IgG
  • Application Notes

    Approved: IF (1:50 - 1:500), IHC, IHC-P (1:100 - 1:500)

    Usage: Immunohistochemistry: Antigen retrieval is recommended. Antigen retrieval with citrate buffer will enhance staining. Likely to work with frozen sections. In some cases, the antibody may be diluted further than indicated. Human controls: Colon Carcinoma, Testicular Seminoma. Mouse controls: Testis.

    Comment

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    Tris-buffered saline, 0.1 % BSA, 0.09 % sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C

    Storage Comment

    Store at 2-8°C for up to 1 year.

    Expiry Date

    12 months
  • Target

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    Alternative Name

    CHEK1 / CHK1

    Background

    Name/Gene ID: CHEK1
    Subfamily: NIM1
    Family: Protein Kinase

    Synonyms: CHEK1, CHK1 checkpoint homolog, Cell cycle checkpoint kinase, Checkpoint kinase 1, CHK1, Chk1-S, Protein kinase chk1, Checkpoint kinase-1

    Gene ID

    1111

    Pathways

    p53 Signaling, Apoptosis, Cell Division Cycle, DNA Damage Repair
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