GRIA2 antibody (AA 175-430)

Catalog No. ABIN199199

Product Details anti-GRIA2 Antibody

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Binding Specificity: AA 175-430

Reactivity: Rat, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This GRIA2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Radioimmunoassay (RIA)

Specificity: Recognizes rat Glutamate Receptor 2 (GluR2) at 102kD. Other proteins (66kD or lower MW) appear to be breakdown products of GluR2. In IHC, GluR2 is widely distributed at both the cellular and synaptic levels. Recognizes GluR2 present in a vast majority of, but not all, GABAergic interneurons. Does not cross-react with other AMPA/Kainate GluR subunits. Species cross-reactivity: Macaque monkey and canine.

Purification: Protein A purified

Immunogen: Recombinant fusion protein TrpE-GluR2 (putative N-terminal portion, aa175-430).

Type of Immunogen: Recombinant protein

Clone: 6C4

Isotype: IgG2a

Application Details

Application Notes: Approved: ELISA, ICC, IHC, RIA, WB

Usage: Suitable for use in Immunohistochemistry, Western Blot, ELISA, Immunocytochemistry and RIA. Immunohistochemistry (50um 4 % paraformaldehyde fixed tissue): 1:250-1:400. Immunocytochemistry: 4 % paraformaldehyde fixed cells. Positive control: Cerebral cortex, pyramidal neurons.

Comment:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 40 % glycerol. No preservatives added.

Preservative: Without preservative

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Target Details for GRIA2

Target: GRIA2 (Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2))

Alternative Name: GRIA2 / GLUR2 (GRIA2 Products)

Synonyms: GLUR2 antibody, GLURB antibody, GluA2 antibody, GluR-K2 antibody, HBGR2 antibody, GluR-2 antibody, GluR-B antibody, Glur-2 antibody, Glur2 antibody, GluR2 antibody, gluR-B antibody, glur2a antibody, gria2.1 antibody, zfGRIA2[a] antibody, glur2 antibody, glutamate ionotropic receptor AMPA type subunit 2 antibody, glutamate receptor, ionotropic, AMPA 2 antibody, glutamate receptor, ionotropic, AMPA2 (alpha 2) antibody, glutamate receptor, ionotropic, AMPA 2a antibody, glutamate receptor, ionotropic, AMPA 2 S homeolog antibody, GRIA2 antibody, Gria2 antibody, gria2a antibody, gria2.S antibody

Background: Name/Gene ID: GRIA2
Subfamily: Glutamate receptor - ionotropic (NMDA receptor)
Family: Ion Channel

Synonyms: GRIA2, AMPA 2, GluR-K2, Glutamate receptor 2, HBGR2, GluA2, GluR-2, GluR-B, GLUR2, GLURB

Gene ID: 2891

UniProt: P42262

Pathways: PI3K-Akt Signaling