Lamin A/C antibody (AA 598-611)

Catalog No. ABIN201197

The Mouse Monoclonal anti-Lamin A/C antibody has been validated for WB, IHC, ICC, FACS and IHC (fro). It is suitable to detect Lamin A/C in samples from Human, Mouse, Rat, Cow and Dog.

Quick Overview for Lamin A/C antibody (AA 598-611) (ABIN201197)

Target: Lamin A/C (LMNA)

Reactivity: Human, Mouse, Rat, Cow, Dog

Host: Mouse

Clonality: Monoclonal

Conjugate: This Lamin A/C antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-Lamin A/C Antibody

Binding Specificity: AA 598-611

Specificity: Reacts with lamin A exclusively, epitope located between aa598-611. Species cross-reactivity: Human, mouse, rat, bovine, and canine.

Purification: Purified

Immunogen: Recombinant human Lamin A.

Type of Immunogen: Recombinant protein

Isotype: IgG3 kappa

Application Details

Application Notes: Approved: Flo (1:100 - 1:200), ICC, IHC, IHC-Fr, WB (1:100 - 1:1000)

Usage: Suitable for use in Immunocytochemistry, Flow Cytometry, Immunohistochemistry and Western Blot. Immunocytochemistry: Frozen sections. Flow Cytometry: 1:100-1:200. Immunohistochemistry: 1:100-1:200, Frozen sections, Use ABC detection system. Western Blot: 1:100-1:1000. Optimum dilutions to be determined by researcher. Hybridoma: Hybridization of P3/X63. Ag8.653 myeloma cells with spleen cells from Balb/c mice.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.2, 0.09 % sodium azide. No stabilizing proteins added.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Target Details for Lamin A/C

Target: Lamin A/C (LMNA)

Alternative Name: LMNA / Lamin A/C

Background: Name/Gene ID: LMNA

Synonyms: LMNA, 70 kDa lamin, CDCD1, CMD1A, EMD2, FPLD, IDC, FPL, FPLD2, Lamin A/C, Lamin, LFP, LMNC, LMN1, LMNL1, HGPS, Prelamin-A/C, PRO1, Lamin A, Lamin A/C-like 1, LGMD1B, CDDC, CMT2B1, LDP1

This antibody detects: LMNA / Lamin A+C

Gene ID: 4000

UniProt: P02545

Pathways: Apoptosis, Caspase Cascade in Apoptosis, ER-Nucleus Signaling, Protein targeting to Nucleus