Caspase 8 antibody (N-Term)

Catalog No. ABIN202629

This anti-Caspase 8 antibody is a Rabbit Polyclonal antibody detecting Caspase 8 in WB. Suitable for Human, Mouse, Rat, Cow, Monkey and Dog.

Quick Overview for Caspase 8 antibody (N-Term) (ABIN202629)

Target: Caspase 8 (CASP8)

Reactivity: Human, Mouse, Rat, Cow, Monkey, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Caspase 8 Antibody

Binding Specificity: N-Term

Specificity: Human CASP8 / Caspase 8

Predicted Reactivity: Percent identity by BLAST analysis: Human, Bovine (100%) Horse (93%) Dog (86%) Mouse, Rat (80%).

Purification: Protein A purified

Immunogen: Synthetic peptide from N-Terminus of human CFLAR (O15519, NP_003870). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Marmoset, Rat, Bovine (100%), Galago, Elephant, Horse (93%), Dog, Bat (86%), Mouse (80%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (1.25 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

NCBI Accession: NP_003870

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades