Integrin beta 2 antibody

Catalog No. ABIN206736

This anti-Integrin beta 2 antibody is a Rat Monoclonal antibody detecting Integrin beta 2 in FACS, IP, IHC, IHC (fro) and BR. Suitable for Human and Dog.

Quick Overview for Integrin beta 2 antibody (ABIN206736)

Target: Integrin beta 2 (ITGB2)

Reactivity: Human, Dog

Host: Rat

Clonality: Monoclonal

Conjugate: This Integrin beta 2 antibody is un-conjugated

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR)

Clone: YFC118-3

Product Details anti-Integrin beta 2 Antibody

Specificity: Recognizes the human CD18 cell surface antigen, the integrin beta2 subunit. CD18 is expressed by the majority of leucocytes. Blocks CD18 mediated homotypic adhesion.

Purification: Purified

Immunogen: Human neutrophils.

Type of Immunogen: Cells

Isotype: IgG2b

Application Details

Application Notes: Approved: Block, Flo (1:50 - 1:100), IHC, IHC-Fr (1:1000 - 1:5000), IP

Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: 4°C or -20°C, Avoid freeze-thaw cycles.

Target Details for Integrin beta 2

Target: Integrin beta 2 (ITGB2)

Alternative Name: ITGB2 / MAC-1 / CD18

Background: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

Gene ID: 3689

Pathways: NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation