CD11b antibody
Quick Overview for CD11b antibody (ABIN206947)
Target
See all CD11b (ITGAM) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Specificity
- Recognizes CD11b antigen (Mac-1), a 165 kD type 1 transmembrane protein mainly expressed on monocytes, granulocytes and NK-cells. The CD11b mediates neutrophil and monocyte interactions with stimulated endothelium.
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Purification
- Protein A purified
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Immunogen
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Human granulocytes.
Type of Immunogen: Cells -
Isotype
- IgG2a
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anti-Integrin alpha M (ITGAM) (AA 145-340) antibody
ITGAM Reactivity: Human IHC, WB, IF Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 520-570) antibodyITGAM Reactivity: Human, Mouse, Rat FACS Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 253-282), (N-Term) antibodyITGAM Reactivity: Human FACS, WB, IHC (p) Host: Rabbit Polyclonal RB17991 unconjugated
anti-Integrin alpha M (ITGAM) (AA 77-180) antibodyITGAM Reactivity: Human, Mouse, Rat FACS, WB, IHC (fro), ELISA, IHC (p), IF (cc), IF (p) Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) (AA 31-160) antibodyITGAM Reactivity: Rat IHC, WB, IP, ICC Host: Rabbit Polyclonal unconjugated
anti-Integrin alpha M (ITGAM) antibody (FITC)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 FITC
anti-Integrin alpha M (ITGAM) antibody (Biotin)ITGAM Reactivity: Human FACS, IP Host: Mouse Monoclonal MEM-174 Biotin
anti-Integrin alpha M (ITGAM) antibody (PE)ITGAM Reactivity: Human FACS Host: Mouse Monoclonal MEM-174 PE
anti-Integrin alpha M (ITGAM) (AA 623-728) antibodyITGAM Reactivity: Human ICC, ELISA Host: Mouse Monoclonal 3A10H5 unconjugated
anti-Integrin alpha M (ITGAM) (AA 941-1074) antibodyITGAM Reactivity: Human IHC, WB, StM Host: Mouse Monoclonal ITGAM-3340 unconjugated
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Application Notes
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Approved: Flo, IP
Usage: Flow Cytometry: Recommended dilution - 1 μg/mL. Positive control - Peripheral Blood Lymphocytes. Immunoprecipitation: Positive control - Granulocytes. CD11b/CD18 transfectants. Application note - Immunoprecipitation with the antibody MEM-174 was successfu -
Comment
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Target Species of Antibody: Human
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- PBS, 15 mM sodium azide, approx, pH 7.4.
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handling Advice
- avoid freeze thaw cycles.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.
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- CD11b (ITGAM) (Integrin alpha M (ITGAM))
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Alternative Name
- ITGAM / CD11b
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Background
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Name/Gene ID: ITGAM
Family: Integrin
Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain -
Gene ID
- 3684
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UniProt
- P11215
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Pathways
- Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
Target
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