CD46 antibody (Biotin)

Catalog No. ABIN207203

The Mouse Monoclonal anti-CD46 antibody has been validated for FACS and IF. It is suitable to detect CD46 in samples from Human and Cow.

Quick Overview for CD46 antibody (Biotin) (ABIN207203)

Target: CD46

Reactivity: Human, Cow

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD46 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS), Immunofluorescence (IF)

Clone: MEM-258

Product Details anti-CD46 Antibody (Biotin)

Specificity: Recognizes an epitope on SCR4 (the membrane-proximal SCR) domain of CD46 (Membrane cofactor protein). CD46 is 56-66 kD dimeric transmembrane protein expressed on T and B lymphocytes, platelets, monocytes, granulocytes, endothelial cells, epithelial cells and fibroblast, it is negative on erythrocytes.

Purification: Protein A purified

Immunogen: HPB-ALL human T cell line.

Type of Immunogen: Cells

Isotype: IgG1

Application Details

Application Notes: Approved: Flo (1:1000), IF (1:1000)

Usage: Biotinylated antibody is designed for indirect immunofluorescence analysis by Flow Cytometry. Suggested working dilution is 1:1000. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by th The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 15 mM sodium azide, approx,  pH 7.4.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: avoid freeze thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Short term 4°C, long term aliquot and store at -20°C, avoid freeze-thaw cycles.

Target Details for CD46

Target: CD46

Alternative Name: MCP / CD46

Background: Name/Gene ID: CD46

Synonyms: CD46, AHUS2, CD46 antigen, MCP, Measles virus receptor, TLX, MIC10, TRA2.10, Membrane cofactor protein

Gene ID: 4179

UniProt: P15529

Pathways: Regulation of Actin Filament Polymerization