Caspase 8 antibody (AA 217-222)

Catalog No. ABIN207902

The Mouse Monoclonal anti-Caspase 8 antibody has been validated for WB and FACS. It is suitable to detect Caspase 8 in samples from Human, Mouse and Monkey.

Quick Overview for Caspase 8 antibody (AA 217-222) (ABIN207902)

Target: Caspase 8 (CASP8)

Reactivity: Human, Mouse, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Caspase 8 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS)

Clone: 90A992

Product Details anti-Caspase 8 Antibody

Binding Specificity: AA 217-222

Specificity: This can be used for detection of the pro-form of Caspase-8.

Predicted Reactivity: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%) Mosquito, Nematode, Arabidopsis, Coccidioides (80%).

Purification: Protein G purified

Immunogen: Amino acids PVETDSEEQPof human Caspase-8 were used as the immunogen for this antibody. Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset (100%), Mosquito, Nematode, Arabidopsis, Coccidioides (80%).

Isotype: IgG1

Application Details

Application Notes: Approved: Flo, WB (0.5 - 2 μg/mL)

Not recommended for: IHC-P

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-80 °C

Storage Comment: Short term: 4°C
Long term: -70°C.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

UniProt: Q14790

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades